Reprogramming of human somatic cells by bacteria
نویسندگان
چکیده
منابع مشابه
Reprogramming by cytosolic extract of human embryonic stem cells improves dopaminergic differentiation potential of human adipose tissue-derived stem cells
The extract of pluripotent stem cells induces dedifferentiation of somatic cells with restricted plasticity. In this study, we used the extract of human embryonic stem cells (hESC) to dedifferentiate adipose tissue-derived stem cells (ADSCs) and examined the impact of this reprogramming event on dopaminergic differentiation of the cells. For this purpose, cytoplasmic extract of ESCs was prepare...
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Somatic cells can be reprogrammed to a pluripotent stem-cell state by ectopic expression of defined proteins. However, existing reprogramming methods take several weeks, suffer from low efficiencies, and most use DNA-based vectors, which carry mutagenesis risks. Here, we describe efficient and rapid reprogramming of human cells using RNA. Within two weeks, fibroblasts from 7 adult patients, inc...
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ژورنال
عنوان ژورنال: Development, Growth & Differentiation
سال: 2015
ISSN: 0012-1592
DOI: 10.1111/dgd.12209